Advanced Urology Procedures: RIRS, PCNL, Laser Prostate & Ureteroscopy in Mumbai | Dr. Anand Utture
Expert Medical Insights · Mumbai

Advanced Urology Procedures: Laser Technology & Minimally Invasive Care

A comprehensive guide to how advanced laser technology and minimally invasive procedures are transforming urological care — from RIRS and PCNL for kidney stones to laser prostate surgery and flexible ureteroscopy — by Dr. Anand Utture, leading urologist in Mumbai.

Dr. Anand Utture, Urologist Mumbai 15 min read June 2026
Kidney Stones

What is RIRS surgery for kidney stones?

Retrograde Intrarenal Surgery (RIRS) is a state-of-the-art, incision-free procedure for treating kidney stones located within the kidney itself. Using a flexible digital ureteroscope — a thin, steerable camera thinner than a pencil — the surgeon navigates through the natural urinary passage (urethra → bladder → ureter → kidney) to reach the stone directly, without making a single cut in the body. A laser fibre is then passed through the scope to pulverise the stone into fine dust that passes naturally in urine.

RIRS has become the procedure of choice for stones up to 2 cm in Mumbai's leading urology centres. Dr. Anand Utture performs RIRS using the latest single-use digital flexible ureteroscopes paired with holmium or thulium fibre laser systems — delivering higher stone-free rates with a complication profile that approaches zero.

No incision

The entire procedure is performed through the natural urinary tract. No skin cuts, no stitches, no external scars of any kind.

Day-care surgery

Most patients are discharged the same day or after a single overnight stay, making RIRS ideal for working professionals and those who cannot afford extended absence from work.

Rapid recovery

Patients typically return to desk work within 2–3 days and resume full activity by day 5–7. There are no activity restrictions beyond the first week.

Minimal bleeding

Because no tissue is cut or punctured, blood loss is negligible. RIRS is the safest surgical option for patients on anticoagulants or with a single functioning kidney.

All stone locations

RIRS can access every calyx of the kidney — including the lower pole, which is difficult to treat with shock-wave lithotripsy (ESWL) — making it far more versatile than non-surgical alternatives.

Safe for complex cases

Suitable for patients with solitary kidney, horseshoe kidney, bleeding disorders, obesity, and those who have previously failed ESWL. The risk profile is the same regardless of patient complexity.

How RIRS is performed — step by step

  1. Pre-operative evaluation

    A CT urogram maps the stone's exact size, location, and density. Urine culture rules out infection. Blood tests assess kidney function. A ureteral stent is sometimes placed 1–2 weeks prior to dilate the ureter for easier scope passage.

  2. Anaesthesia and positioning

    The procedure is performed under general or spinal anaesthesia. The patient lies in the lithotomy position (on their back, legs elevated) — the same as for routine cystoscopy.

  3. Scope navigation to the kidney

    The flexible ureteroscope is passed through the urethra, into the bladder, up the ureter, and into the renal pelvis. Real-time fluoroscopic guidance confirms position. The entire navigation takes under five minutes in experienced hands.

  4. Laser lithotripsy

    A 200–272 micron holmium or thulium fibre laser is deployed through the working channel. Laser pulses fragment the stone into dust particles smaller than 1 mm (the "dusting" technique), which pass spontaneously in urine over the following days.

  5. Ureteral stent placement

    A temporary double-J stent is placed at the end of the procedure to ensure unobstructed urine drainage while post-operative swelling settles. It is removed under local anaesthesia in the clinic after 1–2 weeks.

  6. Discharge and recovery

    Most patients go home the same evening with oral painkillers and an alpha-blocker to ease stent discomfort. A follow-up ultrasound or X-ray at 4 weeks confirms stone-free status.

Dr. Utture's note: The introduction of single-use digital flexible ureteroscopes has been transformative. Unlike older reusable scopes that degraded with use, single-use scopes deliver consistent optical quality and eliminate cross-infection risk entirely. Every RIRS at my practice in Mumbai uses a sterile, never-before-used scope — the same standard as leading international centres.

Kidney Stones

PCNL surgery: procedure, benefits & recovery

Percutaneous Nephrolithotomy (PCNL) is the gold standard for treating large kidney stones (above 2 cm), staghorn calculi (stones that occupy multiple branches of the kidney's collecting system), and complex stones that cannot be managed with RIRS or ESWL. Despite involving a small incision, modern PCNL — particularly Mini-PCNL (mPCNL) and Ultra-mini PCNL — has become a highly refined, low-complication procedure with excellent stone-clearance rates.

Standard PCNL

Percutaneous Nephrolithotomy
Access sheath24–30 Fr (8–10 mm)
Incision~10 mm
Hospital stay2–3 days
Recovery7–10 days
Bleeding riskModerate
Best forStaghorn calculi, very large stones

What to expect: before, during, and after PCNL

  1. Pre-operative workup

    CT urogram defines stone burden, anatomy, and access planning. Urine must be sterile (culture-negative) before surgery. Blood group, cross-match, coagulation screen, and renal function are assessed. Anticoagulants are paused according to standard protocols.

  2. Prone positioning and access

    Under general anaesthesia, the patient lies face down (prone). A ureteral catheter is passed to opacify the collecting system. Using fluoroscopic and/or ultrasound guidance, a needle is advanced through the back skin into the kidney under real-time imaging — a step that demands considerable experience to minimise risk.

  3. Tract dilation and sheath placement

    The needle track is progressively dilated over a guidewire to accept the working sheath (14–30 Fr depending on technique). The nephroscope is then passed through this sheath directly into the kidney.

  4. Stone fragmentation and extraction

    Using an ultrasonic, pneumatic, or laser lithotripter, stones are broken into fragments under direct vision. Larger fragments are grasped and removed; smaller pieces are washed out. The entire collecting system is inspected to confirm clearance.

  5. Nephrostomy tube placement

    A small nephrostomy drainage tube may be left through the access tract overnight to drain residual debris and allow post-operative imaging. In selected cases ("tubeless PCNL"), no tube is placed, reducing discomfort and allowing same-day discharge.

  6. Post-operative imaging and discharge

    A plain X-ray or CT the following morning confirms stone clearance. The nephrostomy tube, if placed, is removed before discharge. Most patients are home within 24–48 hours and return to work within one week.

Key insight: PCNL stone-free rates exceed 85–95% for large and complex stones in a single procedure — far superior to ESWL (40–60%) or RIRS alone for stones above 2 cm. For patients with staghorn calculi that would previously have required open surgery, modern PCNL offers complete stone clearance through a 5 mm access point.

Prostate

Laser surgery for enlarged prostate explained

For men whose benign prostatic hyperplasia (BPH) does not respond adequately to medication, laser prostate surgery has become the preferred surgical option at leading urology centres worldwide — including Dr. Utture's practice in Mumbai. Laser procedures offer the efficacy of open prostatectomy with a fraction of the blood loss, a shorter hospital stay, and a faster return to daily activity.

Three laser techniques are in clinical use. The choice between them depends on prostate size, surgeon expertise, and patient factors:

HoLEP — Holmium Laser Enucleation

The gold standard for all prostate sizes. The holmium laser precisely enucleates (shells out) the entire transition zone — the tissue that causes obstruction — along anatomical planes. Tissue is retrieved for pathological analysis. Suitable for prostates of any size, including very large glands above 150 mL.

ThuLEP — Thulium Laser Enucleation

A newer alternative to HoLEP using a thulium fibre laser, offering continuous-wave energy delivery for smoother tissue incision and haemostasis. Outcomes and safety profile are equivalent to HoLEP; surgeon experience determines the choice.

GreenLight PVP — Photoselective Vaporisation

A KTP laser vaporises prostate tissue without retrieving it. Best suited for moderate-sized prostates (under 80 mL) in men on anticoagulants. Shorter operative time, but no tissue for histology and higher retreatment rates for large glands compared to HoLEP.

Key advantages of laser prostate surgery over conventional TURP

  • Safe on anticoagulants — The laser seals blood vessels as it cuts. Patients on warfarin, aspirin, or newer anticoagulants (rivaroxaban, apixaban) can undergo HoLEP without stopping their blood-thinning medication — a critical advantage for elderly men with cardiac conditions.
  • No size limit — HoLEP and ThuLEP can treat prostates of 30 mL to over 300 mL with equal safety and efficacy. Standard TURP is limited to approximately 80 mL before operative risk increases significantly.
  • Catheter removal within 24 hours — Most patients have their urinary catheter removed the morning after surgery and are discharged that day, compared to 3–5 days for conventional TURP.
  • Extremely low retreatment rate — Because the entire obstructing tissue is removed (enucleation rather than partial resection), the risk of symptom recurrence is under 2% at 10 years — the lowest of any BPH surgical technique.
  • Tissue available for cancer detection — Unlike vaporisation techniques, HoLEP retrieves all removed tissue for pathological examination, allowing incidental prostate cancer to be detected in approximately 5–8% of cases.
  • No TUR syndrome risk — Conventional TURP uses hypotonic irrigating fluid that can cause dangerous electrolyte disturbance (TUR syndrome) in long cases. Laser enucleation uses saline, completely eliminating this risk.

Dr. Utture's note: HoLEP is technically demanding and has a well-documented learning curve. The outcomes it delivers — near-zero blood transfusion rates, day-care surgery, and durability exceeding any other BPH procedure — are only realised in the hands of a surgeon who performs it regularly. When considering laser prostate surgery in Mumbai, ask your urologist specifically how many HoLEP procedures they have performed.

Endourology

Flexible ureteroscopy: what patients should know

Flexible ureteroscopy (fURS) is the foundational technology that makes RIRS and many other minimally invasive urological procedures possible. A flexible ureteroscope is a thin (2.5–3.3 mm diameter), steerable fibre-optic or digital camera that can navigate the entire urinary tract — from the urethra all the way to every corner of the kidney — without any incision. Understanding how this technology works helps patients appreciate what makes modern urology so transformative.

Digital imaging

Latest scopes use a CMOS chip at the tip for HD video — superior to traditional fibre-optic bundles

270° deflection

The tip bends in all directions, reaching even the most inaccessible lower-pole calyx

Working channel

A 3.6 Fr channel allows passage of laser fibres, baskets, and biopsy tools simultaneously

Single-use

Sterile, disposable scopes used at Dr. Utture's practice eliminate cross-infection and maintain consistent performance

Clinical applications of flexible ureteroscopy

Kidney stone treatment (RIRS)

The primary application. Laser lithotripsy through a flexible scope is the preferred treatment for intrarenal stones up to 2 cm, with stone-free rates exceeding 90% in experienced hands.

Ureteral stones

Stones in any part of the ureter — upper, mid, or lower — are directly visualised and lasered. Ureteroscopy achieves stone-free rates above 95% for ureteral calculi, outperforming ESWL significantly.

Upper tract biopsy

Suspicious lesions in the ureter or renal pelvis can be biopsied under direct vision without open surgery, enabling diagnosis of upper tract urothelial carcinoma at an early, curable stage.

Ureteral stricture treatment

Endoscopic incision (endoureterotomy) of benign ureteral strictures — often caused by prior surgery or stone passage — can restore normal drainage without open surgical reconstruction.

Diagnostic ureteroscopy

Unexplained blood in urine (haematuria) with normal CT findings is investigated by directly inspecting the ureter and renal collecting system for small lesions invisible on imaging.

Post-PCNL residual fragments

Small stone fragments remaining after PCNL can be cleared in a second-look flexible ureteroscopy, achieving complete stone-free status without a further percutaneous access.

Key insight: The "ureteroscope" available at most general hospitals in Mumbai remains a rigid or semi-rigid instrument suitable only for lower-ureteral stones. A true flexible digital ureteroscope — capable of reaching the kidney and all its calyces — is available only at centres with dedicated endourology infrastructure. Always confirm that the scope being used for your procedure is a genuinely flexible instrument.

Patient Benefits

Benefits of minimally invasive urology procedures

The shift from open surgery to minimally invasive endourology over the past two decades represents one of the most significant advances in surgical medicine. For patients, the difference is transformative — what once required a week-long hospitalisation and months of recovery can now be achieved through a natural body passage or a 5 mm incision, with a return to work measured in days. Here is what the evidence and clinical experience consistently show:

Shorter hospital stays

RIRS: same-day or 1-night. Mini-PCNL: 1–2 nights. HoLEP: 1–2 nights. Open surgery for equivalent conditions: 5–10 nights. The impact on personal and professional life is enormous.

Faster return to activity

Most minimally invasive urological procedures allow return to desk work within 3–5 days and full activity within 1–2 weeks. Open surgery typically requires 4–6 weeks before resuming normal life.

Drastically reduced blood loss

Blood transfusion is virtually never required for RIRS, flexible ureteroscopy, or HoLEP. For PCNL, transfusion rates have fallen from 10–20% with open surgery to under 2% with modern Mini-PCNL.

No or minimal scarring

RIRS and flexible ureteroscopy leave no external marks whatsoever. PCNL access is a 5–10 mm puncture that heals to an inconspicuous mark. HoLEP leaves no abdominal scar.

Lower infection risk

Smaller wounds mean less exposure to environmental pathogens. Closed-system endoscopic procedures maintain a sterile irrigant environment throughout, reducing surgical site infection rates compared to open cases.

Safer for high-risk patients

Shorter operative times, lower blood loss, and reduced physiological stress make minimally invasive procedures feasible for elderly patients, those with cardiac disease, and patients on anticoagulants who would be unacceptably high-risk for open surgery.

Less post-operative pain

Without large incisions or retraction of muscles and organs, post-operative pain is significantly lower. Most patients require only oral analgesics for 2–3 days after RIRS or HoLEP — no epidurals, no PCA pumps, no intravenous opioids.

Equivalent or superior outcomes

Stone-free rates for RIRS and PCNL match or exceed open surgery. HoLEP's long-term BPH results are superior to TURP with a 10-year retreatment rate under 2%. Minimally invasive is not a compromise — it is an upgrade.

Open surgery vs minimally invasive urology: at a glance

Open Surgery

Traditional approach
Incision10–20 cm
Hospital stay5–10 days
Recovery4–6 weeks
Blood lossSignificant
Pain levelHigh
ScarringLarge, permanent
High-risk patientsOften contraindicated

Dr. Utture's note: At my practice in Mumbai, open urological surgery for kidney stones and BPH is essentially never performed. Every patient — regardless of stone size, prostate size, or medical complexity — is evaluated for a minimally invasive solution first. In the vast majority of cases, one is available. The era of large urological incisions is over.

AU

Consult Dr. Anand Utture — Best Urologist in Mumbai

With extensive expertise in RIRS, PCNL, HoLEP, flexible ureteroscopy, and the full spectrum of minimally invasive endourology, Dr. Anand Utture provides advanced, evidence-based urological care to patients across Mumbai, Thane, and Maharashtra.

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Frequently asked questions

What is RIRS surgery and when is it used?

RIRS (Retrograde Intrarenal Surgery) treats kidney stones up to 2 cm through the natural urinary passage — no incision, 1-day hospital stay, 3–5 day recovery. A flexible ureteroscope delivers laser energy to pulverise the stone into dust that passes naturally in urine.

What is PCNL and how does it differ from RIRS?

PCNL (Percutaneous Nephrolithotomy) accesses the kidney through a small 5–10 mm back incision and is used for large stones above 2 cm and complex staghorn calculi. Modern Mini-PCNL achieves stone-free rates of 85–95% with a 1–2 day hospital stay. RIRS is preferred for smaller stones; PCNL for larger ones.

What is laser surgery for the prostate (HoLEP)?

HoLEP uses a holmium laser passed through the urethra to remove the entire obstructing prostate tissue without any external incision. It is suitable for prostates of any size, involves minimal bleeding, a 1–2 day hospital stay, and has the lowest long-term retreatment rate of any BPH surgery.

What is flexible ureteroscopy used for?

A flexible ureteroscope is a steerable camera passed through the natural urinary tract to treat kidney and ureteral stones (RIRS), biopsy suspicious upper-tract lesions, treat ureteral strictures, and investigate unexplained blood in urine — all without any incision.

What are the benefits of minimally invasive urology procedures?

Compared to open surgery, minimally invasive procedures offer shorter hospital stays (same-day to 2 nights), faster recovery (days rather than weeks), minimal blood loss, no large scars, lower infection risk, less pain, and outcomes that are equivalent or superior. They are also feasible in high-risk patients who cannot tolerate open surgery.

Who is the best urologist in Mumbai for advanced endourology?

Dr. Anand Utture is widely regarded as one of the best urologists in Mumbai, with extensive experience in RIRS, PCNL, HoLEP, flexible ureteroscopy, and the full spectrum of minimally invasive endourology. He offers advanced, evidence-based urological care to patients across Mumbai and Maharashtra.

Medical disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified urologist for diagnosis and treatment of urological conditions. For appointments with Dr. Anand Utture in Mumbai, please visit dranandutture.com.

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